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目的:观察黄芪注射液与苯那普利联用对慢性肾小球肾炎患者蛋白尿、肾功能和血压等的影响。方法:将患者随机分为两组,均给予常规综合治疗。治疗组加用黄芪注射液30ml(相当于生药60g),加入5％葡萄糖液250ml中静脉滴注.每日1次,苯那普利5～20mg,每日1次;对照组加用硝苯地平10mg,每日3次,盐酸可乐定0.075mg,每日3次。疗程均为4周。结果:治疗组尿蛋白较治疗前下降66.6％,对照组较治疗前下降48.7％,两组比较治疗组明显优于对照组。结论:黄芪注射液与苯那普利联用具有降压及保护肾功能、降低蛋白尿的作用。
Objective: To observe the effects of astragalus injection combined with benazepril on proteinuria, renal function and blood pressure in patients with chronic glomerulonephritis. Methods: The patients were randomly divided into two groups, were given conventional comprehensive treatment. Treatment group plus Astragalus injection 30ml (equivalent to crude drug 60g), add 5% glucose solution 250ml intravenous infusion. Daily benazepril 5 ~ 20mg, day 1; control group plus nifedipine Level 10mg, 3 times a day, clonidine hydrochloride 0.075mg, 3 times a day. The course of treatment is 4 weeks. Results: The urinary protein in the treatment group decreased by 66.6% compared with that before treatment, while the control group decreased by 48.7% compared with that before treatment. The two groups were significantly better than the control group. Conclusion: Astragalus injection and benazepril combined with antihypertensive and protect renal function, reduce the role of proteinuria.