盐酸吗啉吡咯酮(Doxapram hydrochloride)是一种呼吸兴奋剂,已证明可增加中央和周围肺潮气量,并轻微增加换气率。据报道,腹部手术后立即经静脉注入盐酸吗啉吡咯酮,可减低病人的低氧血症程度,同时还可增加肺每分钟的呼吸量,但也有人持怀疑看法。为了验证吗啉吡咯酮究竟能否预防手术后呼吸的并发症,作者进行了随机和双盲对照的临床试验。 Doxapram hydrochloride is a respiratory stimulant that has been shown to increase tidal volume in the central and peripheral lungs and slightly increase ventilation. It has been reported that intravenous injection of morpholine pyrrolizidine hydrochloride immediately after abdominal surgery can reduce the degree of hypoxemia in the patient and at the same time increase the breathing rate of the lungs per minute. However, some people are still skeptical. To verify whether morpholinopyr did prevent postoperative respiratory complications, the authors conducted randomized and double-blind controlled clinical trials.