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盆腔、腹腔手术后肠粘连、肠梗阻及再次手术带来的困难是各种腹腔手术后最常见而且很难处理和避免的问题。目前尚无有效的预防方法。本文通过31只家兔的动物实验,制造腹腔粘连后用皮尔复液灌洗,盐水对照实验。两周后再次打开腹腔,观察腹腔粘连情况,并切取原粗糙面未粘连肠段及粘连肠段切片观察。用药组腹腔粘连数明显少于对照组,经统计学处理两组有非常显著性差异。病理切片可见给药组粗糙面表面形成连续完整的浆膜组织,而对照组有间皮组织出现但不完整,粘连侧主要是数量不等的纤维结缔组织,少见间皮组织。皮尔复液是预防盆腹腔粘连的有效药物。本文就手术后造成粘连的原因、预防措施、皮尔复液的药理作用、预防粘连的机理进行了探讨。
Pelvic, abdominal adhesions after abdominal surgery, intestinal obstruction and re-operation of the difficulties caused by a variety of abdominal surgery is the most common and difficult to deal with and avoid problems. There are currently no effective prevention methods. In this paper, animal experiments of 31 rabbits, peritoneal adhesions made after the lavage fluid perfusion, saline control experiments. Open the abdominal cavity again two weeks later, observe the abdominal adhesions, and cut the original rough surface of non-adhesion intestinal segment and intestinal segment observation. The number of intraperitoneal adhesions in the treatment group was significantly less than that in the control group, and there was a significant difference between the two groups by statistical analysis. The pathological section showed that the surface of the roughened surface of the drug-treated group formed a continuous and complete serosal tissue, while the control group had the mesothelial tissue but incomplete. The number of adhesions side was mainly fibrous connective tissue with few mesothelial cells. Peel complex liquid is to prevent tubal adhesions effective drugs. In this paper, the causes of adhesions after surgery, preventive measures, the pharmacological effects of Peel liquid, the mechanism of preventing adhesions were discussed.