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目的 探讨可能引起支架内再狭窄的临床及支架相关因素。方法 选择随访的冠状动脉造影资料较全的 137例支架术后患者。依冠状动脉造影结果将其分为支架内再狭窄组和非再狭窄组 ,然后对可能引起支架内再狭窄的临床和支架相关因素在两组中进行对比分析。结果 两组年龄、吸烟、饮酒等情况相似 ,高血压病及糖尿病的发生率差异无显著性。再狭窄组术前靶血管狭窄程度较非再狭窄组重 ,分别为 91%± 7%和 88%± 14% (P =0 0 33)。再狭窄组所选支架的平均直径较非再狭窄组的小 ,分别为 (3 19± 3 90 )mm和 (3 6 3± 0 30 )mm(P =0 0 0 5 ) ;支架长度却较非再狭窄组的长 ,分别为 (2 1 91± 8 98)mm和 (18 2 0± 6 0 7)mm(P =0 0 11)。再狭窄组的支架扩张总时间明显短于非再狭窄组 ,分别为 (2 2 74± 19 5 6 )s和 (2 9 12± 2 5 72 )s(P =0 0 2 6 )。两组的支架扩张次数和扩张压力差异无显著性。结论 本文资料提示年龄、吸烟、饮酒、高血压病、糖尿病、支架扩张次数及压力的大小等因素对支架内再狭窄无明显影响 ,但术前靶血管狭窄程度和支架长度与支架内再狭窄呈正相关 ,而支架直径和支架扩张总时间则呈负相关。
Objective To investigate the clinical and stent-related factors that may cause in-stent restenosis. Methods A total of 137 patients with postoperative coronary angiography were selected. According to coronary angiography results were divided into in-stent restenosis group and non-restenosis group, and then may cause stent restenosis clinical and stent-related factors were compared between the two groups. Results The two groups were similar in age, smoking, alcohol consumption, etc. There was no significant difference in the incidence of hypertension and diabetes between the two groups. The restenosis group had preoperative target vessel stenosis heavier than non-restenosis group, 91% ± 7% and 88% ± 14%, respectively (P = 0.003). The average diameter of the stents selected in the restenosis group was (3 19 ± 3 90) mm and (363 ± 0 30) mm, respectively (P = 0 0 05), less than those in the non-restenosis group The length of non-restenosis group were (2191 ± 898) mm and (1820 ± 670) mm, respectively (P = 0.01). The total stent dilation time was significantly shorter in the restenosis group than in the non-restenosis group (2 2 74 ± 19 5 6) s and (2 9 12 ± 2 5 72) s, respectively (P = 0 0 2 6). There was no significant difference in the number of stent dilatation and dilatation pressure between the two groups. Conclusion The data suggest age, smoking, alcohol consumption, hypertension, diabetes, the number of stent expansion and the size of the pressure and other factors have no significant effect on in-stent restenosis, but the preoperative target vessel stenosis and stent length and in-stent restenosis were positive , While the stent diameter and total stent expansion time was negatively correlated.