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对象和方法 对象:偏头痛患者60例,其中住院18例,门诊42例,诊断标准按照国际头痛学会(IHS)最新制定的偏头痛标准确诊。根据就诊次序按随机数字表随机分为利多卡因组(治疗组)及安慰剂组(生理盐水组)。除外妊娠、发热、精神异常、24小时内饮酒、近期脑外伤及对利多卡因过敏等。利多卡因组32例,男18例,女14例,年龄18~60岁,平均35±9岁,头痛发作持续时间6小时~8天,单侧性头痛22例,双侧性头痛10例。安慰剂组28例,男16例,女12例,年龄17~58岁,平均36±8岁,头痛发作持续时间6小时~7天,单侧性头痛19例,双侧性头痛9例。 方法:头痛发作时让病人取仰卧位,头后仰45°并向头痛侧旋转30°~40°,慢慢经鼻满入2%利多卡因于头痛侧鼻孔内,保持头位2分钟。安慰剂组采用同
Subjects and Methods Subjects: 60 migraineurs, of whom 18 were hospitalized and 42 were diagnosed clinically. The diagnostic criteria were diagnosed according to the latest migraine criteria set by the International Headache Society (IHS). According to the order of treatment according to random number table were randomly divided into lidocaine group (treatment group) and placebo group (saline group). Excluding pregnancy, fever, mental disorders, alcohol consumption within 24 hours, recent brain trauma and allergies to lidocaine. 32 cases of lidocaine group, 18 males and 14 females, aged 18 to 60 years, mean 35 ± 9 years, duration of headache attack 6 hours to 8 days, unilateral headache in 22 cases, bilateral headache in 10 cases . The placebo group of 28 patients, 16 males and 12 females, aged 17 to 58 years, mean 36 ± 8 years, headache duration 6 hours to 7 days, unilateral headache in 19 cases, bilateral headache in 9 cases. Methods: The patient was supine position head back 45 ° and headache side rotation 30 ° ~ 40 °, slowly filled with 2% lidocaine nasal headache side nostrils, head 2 minutes. Placebo group using the same