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目的 :探讨老年口腔癌患者术前全身合并症情况及营养状态对预后的影响。方法 :收集2010年1月—2012年12月间手术治疗的老年(年龄≥60岁)口腔鳞癌患者的相关病史资料,回顾分析合并症指数(Charlson、HNCA、ACT指数)以及营养指数(nutrition index,NI)对术后生存率的影响。采用SPSS 17.0软件包对数据进行统计学分析。结果:465例患者中,死亡170例,Charlson、HNCA以及ACT指数与患者预后(总生存率OS)无相关性(P=0.747、0.530、0.869),术前营养状态与预后相关,营养指数是老年口腔癌患者预后的独立危险因素(P<0.001),得分越高,预后越差。结论:对于老年口腔鳞癌患者,术前全身系统性疾病并不是影响预后的独立因素,术前营养状态越差,生存率越低。
Objective: To investigate the preoperative systemic complications in elderly patients with oral cancer and the impact of nutritional status on prognosis. Methods: The related history data of elderly patients (≥60 years old) with oral squamous cell carcinoma who were surgically treated between January 2010 and December 2012 were collected. The Charlson, HNCA, ACT index and nutrition index were retrospectively analyzed. index, NI) on postoperative survival rate. Data were statistically analyzed using SPSS 17.0 software package. Results: There were 170 deaths among 465 patients. There was no correlation between Charlson, HNCA and ACT index and prognosis of patients (P = 0.747, 0.530, 0.869). Preoperative nutritional status was related to prognosis, and nutritional index was The independent risk factors for the prognosis of elderly patients with oral cancer (P <0.001), the higher the score, the poorer the prognosis. Conclusion: For elderly patients with oral squamous cell carcinoma, preoperative systemic disease is not an independent prognostic factor, the worse the preoperative nutritional status, the lower the survival rate.