结缔组织病(Connective tissue disease,CTD)是一种常见的系统性自身免疫性疾病,包括系统性红斑狼疮、类风湿关节炎等多种疾病,具有多系统受累的特点,病因不明确,临床表现多样,有关结缔组织病与恶性肿瘤的相关性报道较少,为进一步了解两者之间的关系, Connective tissue disease (CTD) is a common systemic autoimmune disease, including systemic lupus erythematosus, rheumatoid arthritis and other diseases, has the characteristics of multiple system involvement, the etiology is not clear, the clinical manifestations Diverse, related to connective tissue disease and malignant tumor less reported, in order to further understand the relationship between the two,