膀胱肿瘤是泌尿系统最常见的肿瘤之一,其发病率呈逐年上升趋势。膀胱肿瘤最常见的病理类型是移行细胞癌(TCC)。目前膀胱癌诊断的金标准是膀胱镜检和病理活检,但其属于创伤性检查,且难于发现早期病变,对预测复发也没有指导意义。因此, 学者们在探索膀胱肿瘤标志物方面作了大量工作, 并取得了一些成果。本文就近年来关于膀胱肿瘤标志物的研究和应用进展作一综述。 Bladder cancer is one of the most common urological tumors and its incidence has been increasing year by year. The most common pathological type of bladder cancer is transitional cell carcinoma (TCC). Currently the gold standard for diagnosis of bladder cancer is cystoscopy and biopsy, but it is a traumatic examination, and difficult to detect early lesions, the prognosis is not guiding significance. Therefore, scholars have done a lot of work in exploring the tumor markers of bladder and achieved some results. This article reviews the research and application progress of bladder tumor markers in recent years.