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丝裂原活性蛋白激磷酸酶 - 1 (Mitogen -activatedproteinkinasephosphatase - 1 ,MKP - 1 )属于MKP家族 ,是由早期应答基因编码的双特异性磷酸酶 ,主要分布于细胞核内 ,在丝裂原蛋白活化激酶MAPK(细胞外信号调节激酶ERK ,p38和c -jun氨基末端激酶JNK)的去磷酸化方面发挥重要作
Mitogen-activated protein phosphatase-1 (MKP-1) belongs to the MKP family and is a bispecific phosphatase encoded by an early response gene, which is mainly distributed in the nucleus and activates mitogen-activated protein Important for dephosphorylation of kinase MAPKs (extracellular signal-regulated kinase ERK, p38 and c-jun amino-terminal kinase JNK)