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为探讨是否通过严格形态学指标能确定有Ph′阴性的慢性粒细胞白血病(COL)病例存在和是否有鉴别PH′阳性和阴性CGL 病例的形态学指标存在,作者对33例CGL 病例(22例Ph′染色体阳性,11例Ph′染色体阴性)进行了研究。所有病人均被收集一般资料(年龄、性别等)。检、测骨髓(BM)标本形态学变化、BM 铁含量变化、网硬蛋白定量,外周血细胞计数及分类计数、血小板计数、染色体形态学检查和诊断结果再评价。
To investigate the presence of Ph ’negative chronic myeloid leukemia (COL) by rigorous morphological tests and the presence or absence of morphological markers for the identification of PH’ positive and negative CGL cases, 33 patients with CGL (22 Ph ’chromosomes were positive and 11 Ph’ chromosomes were negative). All patients were collected general information (age, gender, etc.). The bone morphological changes, changes of BM iron content, quantitative analysis of reticulocyte protein, peripheral blood cell count and classification, platelet count, chromosomal morphological examination and diagnostic results were reviewed.