红花中一种新掺伪染料的确认及6种染色成分检测方法研究

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目的:确认红花药材中一种新掺伪染色的染料成分,并建立所发现的6种染色成分的检测方法。方法:采用制备薄层与液相色谱-质谱联用的方法,对染色成分进行鉴定;建立红花药材中柠檬黄、胭脂红、日落黄、偶氮玉红、酸性红73、金橙Ⅱ6种染色成分的TLC、HPLC、LC-MS检测方法。结果:经与对照品对照,确认红花药材中新发现的染色成分为偶氮玉红;107批红花药材中,31批有掺伪染色现象,其中23批为2种以上染料染色。结论:偶氮玉红首次被发现用于红花药材染色;红花药材染色情况呈现多样化、复杂化趋势。 OBJECTIVE: To identify a newly incorporated dye component of pseudo-dyed safflower and establish the detection methods of the six dyed components found. Methods: The stained components were identified by the method of preparative thin layer and liquid chromatography-mass spectrometry (LC-MS / MS). The contents of lemon yellow, carmine, sunset yellow, azurite, acid red 73, TLC components, TLC, HPLC, LC-MS detection method. Results: Compared with the reference substance, it was confirmed that the newly found dye component of Azolla was Azurite. Of the 107 Hemlock, 31 were adulterated, of which 23 batches were dyed with two or more dyes. CONCLUSION: Azo-jade red was first found for the dyeing of safflower medicinal materials; the safflower medicinal materials showed the tendency of diversification and complication.
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