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目的 探讨胸腺瘤合并重症肌无力患者临床特点及围手术期临床处理方法 .方法 对151例因胸腺瘤接受手术治疗患者的临床资料进行回顾性分析.将61例胸腺瘤合并重症肌无力的患者设为A组,90例单纯胸腺瘤的患者设为B组,比较两组患者的临床资料.结果 两组年龄、病理类型、住院天数和术后并发症比较差异均有统计学意义(P＜0.05或0.01),性别、手术方式、留置胸腔引流管时间、术后胸腺瘤复发率比较差异无统计学意义(P＞0.05).结论 胸腺瘤应及早接受手术治疗,以利于彻底切除肿瘤组织,无论胸腺瘤是否合并重症肌无力,采用胸腺扩大切除术均有利于降低胸腺瘤的术后复发率.“,”Objective To investigate the clinical features and perioperative management of patients with thymoma combined with myasthenia gravis. Methods 151 patients underwent operative treatment of thymoma were retrospectively analyzed.61 cases with thymoma combined with myasthenia gravis were seen as group A, 90 cases with simple thymoma were seen as group B,compare the clinical data of the two groups. Results There were significant differences in the age, pathological type, length of stay and postoperative complications between the two groups (P＜0.05 or 0.01). There were no significant differences in the sex, the mode of operation, the time of indwelling thoracic drainage tube and the recurrence rate of thymoma after operation (P＞0.05). Conclusion Thymoma should be treated early so as to completely remove the tumor tissue. At the same time, thymic enlargement resection can help reduce the recurrence rate of thymoma whether it is combined with myasthenia gravis or not.