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目前,国内外对多糖类的研究方兴未艾,许多研究表明糖类化合物具有较强的免疫刺激和抗肿瘤作用,如云芝多糖能提高荷瘤小鼠腹腔巨噬细胞的舌噬能力,并使因带瘤而降低了的T细胞功能全面恢复,牛膝多糖能提高荷瘤小鼠低下的血清IgG含量,提高其NK细胞活性等,这就为人们从天然植物中寻找出一种毒性低、抗瘤作用强的新药开辟了途径。树舌多糖就是从小兴安岭产树舌中提取的多糖,实验证明它能明显延长L~(7811)白血病和H_(22)小鼠的生存时间,抑制肿瘤胞的生长,为进一步研究其抑瘤作用,本文研究了它对实体型肝癌(HepA)小鼠的抑瘤作用及血清脂质结
At present, research on polysaccharides at home and abroad is in the ascendant. Many studies have shown that sugar compounds have strong immunostimulating and anti-tumor effects. For example, P. oleracea polysaccharide can increase the lingual phagocytic ability of tumor-bearing mice’s peritoneal macrophages, and make Because of the overall recovery of T-cell function that has been reduced by the tumor, Achyranthes bidentata can increase the serum IgG level in the tumor-bearing mice, increase their NK cell activity, etc., which is to find a low toxicity from natural plants. A new drug with a strong anti-tumor effect opens the way. Ganoderma lucidum polysaccharide is a polysaccharide extracted from the tongue of Xiaoxing’anling. It has been proved that it can prolong the survival time of L 7781 leukemia and H 22 mice, inhibit the growth of tumor cells, and further study its anti-tumor effect. This article studied its anti-tumor effect and serum lipid profile in solid Hepatocarcinoma (HepA) mice.