逐渐增大的甲状腺及逐渐发生的甲状腺功能减退是桥本甲状腺炎的典型表现。甲状腺两叶可能不对称,质地坚实,表面光滑或有结节感。患者可因颈部肿胀或新出现的颈部肿块而就诊,但更多的情况是在常规体检或超声检查中被偶然发现。桥本甲状腺炎,也称慢性淋巴细胞性甲状腺炎,是最常见的自身免疫性甲状腺病,好发于30~50岁的女性。病因:存在甲状腺自身抗体在桥本甲状腺炎患者中,抗甲状腺氧化酶抗体(TPOAb)、抗甲状腺球蛋白抗体(TGAb)普遍升高,它们 Increasing thyroid and progressive hypothyroidism is a typical manifestation of Hashimoto’s thyroiditis. Thyroid leaves may be asymmetrical, solid texture, smooth surface or nodular feeling. Patients may have a swollen neck or a newly developed neck mass, but more often they are found accidentally on routine physical or ultrasound exams. Hashimoto’s thyroiditis, also known as chronic lymphocytic thyroiditis, is the most common autoimmune thyroid disease, which occurs in women aged 30 to 50 years. Etiology: The presence of thyroid autoantibodies in patients with Hashimoto’s thyroiditis, anti-thyroid oxidase antibody (TPOAb), anti-thyroglobulin antibody (TGAb) generally increased, they