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耐万古霉素肠球菌(VRE)于1986年第1次被分离,并迅速蔓延至整个美国、欧洲及其他地方.用分子检测技术监测VRE,能快速获得检测结果,有利于预防潜在的VRE感染.在不同的研究中,不同的分子检测方法、或同一分子检测技术的灵敏度、特异度、阳性预测值(PPV)、阴性预测值(NPV)均不同.影响灵敏度、特异度、PPV及NPV的因素多种多样,本研究对以聚合酶链式反应(PCR)为基础的分子生物学方法(MDM)、快速鉴定VRE的研究进展作一综述.“,”Since Firstly isolated in 1986s,vancomycin resistant Enterococci (VRE) has spread throughout the United States,Europe and other places.Molecular detection methods(MDM) for VRE active surveillance can obtain test results quickly,helpful to prevent VRE infection.In different studies,there are many factors resulting in different sensitivity,specificity,positive predictive value (PPV),and negative predictive value(NPV) by different methods or the identical method.Here we present an overview about the research progress in pplymerase chain reaction based methods for rapid identification of VRE.