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偏头痛属于植物神经系统疾病,抗偏头痛药物的研究引起药物学家的兴趣。长期以来多用麦角胺生物碱类进行常规药物治疗,在5-羟色胺(5-HT)受体作用的研究中,5-HTID嫩动剂已经成功地用于偏头痛的治疗,以5-HT结构为基础的活性衍生物必将发展为一类新型的偏头痛治疗剂。本文综述了近年来抗偏头痛药物的研究进展。
Migraine is a disease of the autonomic nervous system and the study of anti-migraine drugs has drawn the interest of pharmacologists. Long-term use of ergotamine alkaloids for routine drug treatment, 5-HT (5-HT) receptor in the study, 5-HTID tender agent has been successfully used for the treatment of migraine, 5-HT structure Based active derivatives is bound to develop into a new class of migraine therapies. This article reviews recent advances in antimigraine drugs.