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目的:研究孕产妇血浆中抗凝血酶Ⅲ与孕产妇脑静脉窦血栓形成(cerebral venous sinus thrombosis,CVST)的关系。方法:以孕产妇脑静脉窦血栓形成患者为研究组,正常孕产妇病例为对照组,通过检测两组孕产妇血浆中抗凝血酶Ⅲ的含量并进行统计学分析。结果:孕产妇脑静脉窦血栓形成患者血浆中的抗凝血酶Ⅲ较正常孕产妇血浆中的抗凝血酶Ⅲ显著降低,差异有统计学意义(P<0.01)。结论:抗凝血酶Ⅲ下降是孕产妇脑静脉窦血栓形成的危险因素之一。
Objective: To study the relationship between antithrombin Ⅲ in maternal plasma and cerebral venous sinus thrombosis (CVST) in pregnant women. Methods: The pregnant women with cerebral venous sinus thrombosis as the research group, the normal pregnant women as the control group, by detecting the two groups of maternal plasma antithrombin Ⅲ content and statistical analysis. Results: Antithrombin Ⅲ in plasma of pregnant women with cerebral venous sinus thrombosis was significantly lower than that of normal pregnant women, the difference was statistically significant (P <0.01). Conclusion: The decline of antithrombin Ⅲ is one of the risk factors of cerebral venous sinus thrombosis in pregnant women.