氨甲喋呤(Methotrexate)对滋养层细胞有毒性作用。低剂量时副作用小。使用它可以治疗妊娠滋养层细胞肿瘤。近来用于治疗宫内孕。在以前的研究中表明除前列腺素外氨甲喋呤可以成功地引起早期妊娠流产。为了证实这个设想10名妊娠42天以内的妇女 Methotrexate has a toxic effect on trophoblast cells. Low dose side effects. Use it to treat gestational trophoblastic tumor. Recently used for the treatment of intrauterine pregnancy. In previous studies, methotrexate other than prostaglandins could successfully induce early pregnancy miscarriage. To confirm that this envisages 10 women within 42 days of pregnancy