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难溶性药物制成固体分散物可使溶出速率加快,吸收增加甲苯磺丁脲(Tolbu-tamide)是一种口服降血糖药,微溶于水,吸收受溶出速率所限。口服后3～4小时血中浓度达峰值。片剂释放度及临床疗效均存
Tolbu-tamide is an oral hypoglycemic agent that is slightly soluble in water and absorbs only as fast as the dissolution rate. 3 to 4 hours after oral administration of blood peak concentration. Tablet release and clinical efficacy of both