在一次对虫生真菌天然色素筛选过程中,发现1株珊瑚虫草分离菌株RCEF4022的菌丝体含黄色色素。采用半制备高效液相色谱方法从该菌甲醇提取物中分离纯化出1种橘黄色物质P-1。高分辨液质联用分析结果表明P-1的分子式为C30H18O12。经化学试剂显色反应以及波谱学方法鉴定,确定P-1为羟基蒽醌类色素2,2’,4,4’,5,5’-hexahydroxy-7,7’-dimethoxy-1,1’-bianthraquinone。该色素化合物尚属首次从虫生真菌中分离得到。 During a natural screening of entomogenous fungi, one mycelium of Coral Cordyceps isolated strain RCEF4022 was found to contain a yellow pigment. A semi-preparative high performance liquid chromatographic method was used to isolate and purify P-1, an orange substance, from the methanol extract of the bacterium. High-resolution LC-MS analysis showed that the molecular formula of P-1 was C30H18O12. The results of chemical reagent chromogenic reaction and spectroscopic identification showed that P-1 was the main anthraquinone pigment of 2,2 ’, 4,4’, 5,5’-hexahydroxy-7,7’-dimethoxy-1,1 ’ -bianthraquinone The pigment compounds for the first time isolated from fungi fungi.