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目的 :观察大剂量丙种球蛋白治疗吉兰 -巴雷综合征 ( GBS)的近期疗效。方法 :对 1 5例 GBS采用丙种球蛋白 0 .4 g.kg- 1 .d- 1 ,静脉注射 5天 ,并与常规激素治疗组对照。结果 :1 5例中 8例痊愈 ,5例改善 (轻残 ) ,2例轴索型 1例留有严重残疾 ,1例无效 ,起效时间及住院日缩短明显 ,两组比较有显著性差异。结论 :大剂量丙种球蛋白是治疗 GBS的有效方法 ,但对轴索损害的 GBS疗效差 ,提示 GBS伴轴索损害者预后不良
Objective: To observe the short-term curative effect of high-dose gamma globulin in the treatment of Guillain-Barre syndrome (GBS). Methods: Fifteen GBSs were given gavage 0.4 g · kg-1 · d-1 intravenously for 5 days and compared with the conventional hormone therapy group. Results: Among 15 cases, 8 cases were cured, 5 cases were improved (mild residual), 1 case had severe disability in 2 cases and 1 case was invalid, and the effective time and hospitalization day were shortened significantly. There was significant difference between the two groups . Conclusion: High-dose gamma globulin is an effective method for the treatment of GBS, but poor efficacy of axonal damage GBS, suggesting that GBS with axonal damage poor prognosis