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目的:探讨影响经皮冠状动脉介入术(PCI)预后的危险因素。方法:371例行PCI成功的冠心病患者根据术后1年是否发生主要心血管事件分为发生组和未发生组,对可能影响PCI预后的危险因素进行多因素Logistic回归分析。结果:单因素分析和多因素Logistic回归分析显示气虚血瘀证、MPA(≥70%)、血浆vWF水平和CYP2C19*2基因突变是影响PCI术后1年主要心血管事件的独立危险因素。结论:气虚血瘀证、血浆vWF水平、MPA70%切割点和CYP2C19*2基因突变对评价PCI预后具有重要意义。
Objective: To investigate the risk factors influencing the prognosis of percutaneous coronary intervention (PCI). Methods: 371 patients with coronary artery disease undergoing PCI were divided into the occurrence group and the non-occurrence group according to whether major cardiovascular events occurred one year after operation. Multivariate Logistic regression analysis was performed on the risk factors that may affect the prognosis of PCI. Results: Univariate analysis and multivariate logistic regression analysis showed that qi deficiency and blood stasis syndrome, MPA (≥70%), plasma vWF level and CYP2C19 * 2 gene mutation were independent risk factors of major cardiovascular events one year after PCI. Conclusion: Qi deficiency and blood stasis syndrome, plasma vWF level, MPA 70% cleavage point and CYP2C19 * 2 gene mutation are of great significance for evaluating the prognosis of PCI.