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目的观察肝动脉化疗栓塞联合三维适形放射治疗原发性肝癌的临床疗效。方法选取2004年1月-2008年12月我院肝癌患者41例,依据患者用药要求不同分为A组14例与B组27例,A组予肝动脉化疗栓塞联合三维适形放射治疗,B组仅予单纯栓塞化疗,比较2组临床疗效。结果 A组近期治疗有效率57.14%,B组为33.33%。但2组比较差异无统计学意义(P>0.05)。结论肝动脉化疗栓塞联合三维适形放射治疗原发性肝癌近期疗效优于单一肝动脉化疗栓塞治疗,且未加重不良反应,无严重放射性肝损伤或放射性肝病,值得进一步研究。
Objective To observe the clinical efficacy of transcatheter arterial chemoembolization combined with three-dimensional conformal radiotherapy in the treatment of primary liver cancer. Methods From January 2004 to December 2008, 41 patients with hepatocellular carcinoma in our hospital were divided into group A (14 cases) and group B (27 cases), group A received hepatic arterial chemoembolization combined with three-dimensional conformal radiotherapy, and group B Group was only simple embolization chemotherapy, the clinical efficacy of two groups were compared. Results The recent treatment efficiency of group A was 57.14% and that of group B was 33.33%. However, there was no significant difference between the two groups (P> 0.05). Conclusions The recent curative effect of transcatheter arterial chemoembolization combined with three-dimensional conformal radiotherapy for primary hepatocellular carcinoma is superior to single transcatheter arterial chemoembolization without serious adverse reactions, no severe radiation-induced liver injury or radiation-induced liver disease, which deserves further study.