我们采用流式细胞术，检测了３８例原发性肾病综合征（ＮＳ）患儿外周血血小板α颗粒膜蛋白（ＣＤ６２Ｐ）、溶酶体膜蛋白（ＣＤ６３）及凝血酶敏感蛋白（ＴＳＰ），同时观察了血管内皮细胞标志，凝血、抗凝及纤溶指标的改变，以探讨血小板活化对ＮＳ的意义。对象和方法１　 We used flow cytometry to detect CD62P, CD63 and thrombospondin (TSP) in peripheral blood of 38 children with primary nephrotic syndrome (NS) At the same time, we observed the changes of vascular endothelial cell markers, coagulation, anticoagulation and fibrinolysis to explore the significance of platelet activation on NS. Objects and methods 1