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目的:分析中药制剂输液不良反应,为临床安全使用中药注射剂提供科学依据。方法:回顾性分析北京航天中心总医院2007-01/2009-06上报的270例中药注射剂不良反应(ADR)报告表。结果:中老年患者不良反应发生率相对较高,中药注射剂引发的不良反应临床表现多样,涉及人体各个系统,包括消化系统、血液系统、循环系统等。临床表现以全身性过敏反应最为多见。结论:应控制药品质量,加强用药观察,严格掌握适应证,使临床用药更加合理,发挥中药注射剂的治疗效果,同时避免不良反应的发生。
Objective: To analyze adverse reactions of transfusion of traditional Chinese medicine preparations and provide scientific basis for clinical safe use of traditional Chinese medicine injection. Methods: A retrospective analysis of 270 cases of Chinese medicine injection adverse drug reaction (ADR) report form reported by Beijing Aerospace Center General Hospital from January 2007 to June 2009 was made. Results: The incidence of adverse reactions in middle-aged and elderly patients was relatively high. The clinical manifestations of adverse reactions caused by Chinese medicine injection were diverse and involved various systems of human body including digestive system, blood system and circulatory system. Clinical manifestations of systemic allergic reactions most common. Conclusion: The quality of medicines should be controlled, the observation of medication should be strengthened, the indications should be strictly controlled, the clinical medication should be more reasonable, the therapeutic effect of traditional Chinese medicine injection should be exerted, and the occurrence of adverse reactions should be avoided.