肠易激综合征(IBS)是胃肠道最常见的功能性疾病,常伴焦虑、忧郁、多疑等症。临床上尚缺乏明确有效的治疗方法,而百忧解是一种高效、高选择的抗抑郁药物,我们1996年2月～1997年5月,对21例伴抑郁症状患者使用百忧解及相应对症治疗,疗效满意。 临床资料 1.对象:根据IBS的诊断标准,入选对象具有如下特点:(1)常有腹痛不适、腹胀、肠鸣、腹泻、便秘和腹泻便秘交替等症状;(2)伴有 Irritable bowel syndrome (IBS) is the most common gastrointestinal tract functional disease, often accompanied by anxiety, depression, suspicious disorders. Clinically, there is a lack of a clear and effective treatment, and Prozac is an effective and highly selective antidepressant drug, we February 1996 ~ May 1997, 21 patients with depressive symptoms using Prozac and the corresponding Symptomatic treatment, efficacy satisfactory. Clinical data 1. Subjects: According to the diagnostic criteria of IBS, the selected subjects have the following characteristics: (1) abdominal discomfort, abdominal distension, bowel, diarrhea, constipation and diarrhea alternating constipation and other symptoms; (2)