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肝性昏迷是肝功能衰竭最严重的表现,是严重肝病患者机体代谢紊乱引起的神经精神功能失调,临床上亦称为肝性脑病。多发生于各型肝硬化、重型病毒性肝炎、中毒性肝炎及慢性肝脏疾患。肝性昏迷的发生可能与肝脏不能清除有毒的代谢产物,脑性毒物在体内增多以及肝脏不能合成维持正常脑代谢或功能所必需的物质等因素有关。此病预后较差,死亡率亦高,因此,及时诊断与正确处理,是改善预后和降低死亡率的关键。一、诊断:主要根据临床表现和实验室检查 (一)原发病和诱因:根据肝脏的原发病变,肝性昏迷可分为急性与慢性两型。慢性型较多
Hepatic coma is the most serious manifestation of liver failure, is a serious liver disease caused by metabolic disorders in neuropsychiatric disorders, clinically known as hepatic encephalopathy. Occur in various types of cirrhosis, severe viral hepatitis, toxic hepatitis and chronic liver disease. The occurrence of hepatic coma may be related to the inability of the liver to remove toxic metabolites, the increase of brain toxicants in the body, and the inability of the liver to synthesize substances necessary to maintain normal brain metabolism or function. The poor prognosis of the disease, the mortality rate is also high, therefore, timely diagnosis and correct treatment is the key to improving prognosis and reduce mortality. First, the diagnosis: mainly based on clinical manifestations and laboratory tests (a) the original disease and incentives: According to the primary liver disease, hepatic coma can be divided into two types of acute and chronic. Chronic type more