恶性肿瘤在无转移的情况下影响全身远隔器官功能,即肿瘤的远隔效应,当神经系统受其影响时,可出现一些各不相同的病征,即副肿瘤综合征(paraneoplastic neurological syn-drome,PNS)。因PNS常在恶性肿瘤临床症状出现之前出现,故误诊率极高。现就1例乳腺癌并发副肿瘤小脑变性报道 Malignant tumors in the absence of metastasis affect remote organ function, that is, the distant effect of the tumor, when the nervous system affected by it, there may be some different symptoms, namely paraneoplastic neurological syn-drome , PNS). Due to PNS often appear before the clinical symptoms of malignant tumors, so the misdiagnosis rate is very high. Now a case of breast cancer complicated with cerebellar degeneration reported