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本文作者测定了34例儿童脾切除前后免疫球蛋白(IgG、IgA和IgM)的浓度。脾切除病人中重型地中海贫血15例,镰状细胞贫血4例,外伤性脾破裂15例(其中10例随访1年,5例随访两年)。对照组为15名年龄相当的健康儿童。所有病儿手术时年龄是2—13岁,术前和术后1、3、6、12、18和24个月时分别测定Ig,其中有7例血液病人测定至术后24和36个月。外伤切脾术前的Ig水平显然不能得到,则采用对照组的Ig值。Ig测定的方法是放射免疫扩散
The authors determined the concentrations of immunoglobulins (IgG, IgA and IgM) in 34 children before and after splenectomy. Fifteen patients with severe thalassemia, four patients with sickle cell anemia, and fifteen patients with traumatic rupture of the spleen (including 10 followed up for 1 year and 5 followed up for 2 years) underwent splenectomy. The control group was 15 healthy children of the same age. All sick children were aged 2-13 years of age at surgery, and preoperative and postoperative 1, 3, 6, 12, 18 and 24 months were measured Ig, of which 7 cases of blood patients measured to 24 and 36 months after surgery . Ig levels before traumatic splenectomy obviously can not be obtained, then the Ig value of the control group. Ig assay is radioimmunoassay