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目的:观察复感宁对治疗小儿反复呼吸道感染(RRTI)非急性感染期的作用。方法:将60例RRTI患儿随机分为2组 各30例。治疗组以复感宁(处方:五瓜龙、茯苓、人参叶、太子参、薏苡仁、鸡内金、生甘草、芒果核)治疗,对照组以核酪口服 液治疗。2组疗程均为8周,停药后随访1月进行疗效评价。结果:临床疗效比较:总有效率治疗组为83.33%,对照组为 70.00%,2组比较,差异无显著性意义(P>0.05)。中医症候疗效比较:总有效率治疗组为93.33%,对照组为60.00%,2组比 较,差异有非常显著性意义(P<0.01)。治疗后治疗组症候积分有明显改善,与治疗前比较,差异有显著性意义(P<0.05),治 疗组与对照组治疗后比较,差异有非常显著性意义(P<0.01)。治疗后体重增加比治疗组为(0.28±0.21)%,对照组为(0.12± 0.08)%,2组比较,差异有非常显著性意义(P<0.01)。结论:复感宁治疗RRTI患儿,能明显改善症状,对减少症候积分、增 加体重较核酪口服液更为明显,是治疗RRTI非急性感染期的有效方剂。
Objective: To observe the effect of Fuganing on non-acute infection of children with recurrent respiratory tract infections (RRTI). Methods: Sixty patients with RRTI were randomly divided into two groups of 30 cases. Treatment group Fufang Ning (prescription: Cucumber, Poria, ginseng leaves, heterophylla, coix seed, chickweed gold, raw licorice, mango nuclear), the control group treated with oral liquid cheese. The two groups were treated for 8 weeks, followed up for 1 month after discontinuation of the efficacy evaluation. Results: The clinical curative effect comparison: The total effective rate was 83.33% in the treatment group and 70.00% in the control group. There was no significant difference between the two groups (P> 0.05). TCM curative effect comparison: The total effective rate was 93.33% in the treatment group and 60.00% in the control group. There was significant difference between the two groups (P <0.01). After treatment, the symptom score of the treatment group was significantly improved, with significant difference compared with that before treatment (P <0.05). There was significant difference between the treatment group and the control group after treatment (P <0.01) . The body weight gain after treatment was (0.28 ± 0.21)% in the treatment group and (0.12 ± 0.08)% in the control group, and there was significant difference between the two groups (P <0.01) . Conclusion: Fuganning treatment of RRTI children can significantly improve the symptoms, reduce the symptom score, increase body weight than the oral liquid more obvious, is the treatment of RRTI non-acute period of effective prescription.