本文论述通过架桥液对分散微粒的附聚作用,可把各种形状的结晶药物改造成为结晶度低、流动性好的球形颗粒,直接压片;亦可用于化学合成,把药物制成可直接压片的球状颗粒;还可把药物附聚成缓释球粒,并把两种药物附聚成具有一定比例且呈零级释放的附聚复合物。这种新技术可望在工业上和药学上得到广泛应用。 This article discusses the bridging solution of agglomeration of dispersed particles, the various shapes of crystalline drugs can be transformed into low crystallinity, good fluidity of spherical particles, direct compression; can also be used for chemical synthesis, the drug can be made Direct compression of the spherical particles; but also the drug agglomeration into sustained release pellets, and the two drugs agglomerate into a certain proportion and agglomeration of the zero-order release of the composite. This new technology is expected to be widely used industrially and pharmacologically.