用左旋氧氟沙星 (Levofloxacin)口服治疗老年人下呼吸道感染 40例 ,并与同期用头孢布烯 (Ceftibuten) 30例作随机平行对照。结果 :两组临床有效率分别为 85 0 %和 83 3% ;细菌清除率分别为 87 1%和 80 0 % ;不良反应发生率分别为 7 5 %和 6 7%。两组疗效和不良反应统计学上均无显著差别 (P >0 0 5 )。从药物经济学角度认为前者显著优于后者 ,表明这两种药是治疗老年人下呼吸道感染的较好选择。 40 cases of lower respiratory tract infection were treated orally with Levofloxacin and 30 cases were treated with Ceftibuten in the same period. Results: The clinical efficacies of the two groups were 85 0% and 83 3% respectively. The bacterial clearance rates were 87 1% and 80 0% respectively. The incidences of adverse reactions were 75% and 67% respectively. There was no significant difference between the two groups in the efficacy and adverse reactions (P> 0.05). The former is significantly superior to the latter from the perspective of pharmacoeconomics, indicating that these two drugs are a better choice for the treatment of lower respiratory tract infections in the elderly.