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Gordon等曾对35～59岁人群血脂的季节性变化作过大系列纵向研究,发现总胆固醇(TC),低密度脂蛋白胆固醇(LDL—C)和高密度脂蛋白胆固醇(HDL—C)的高峰值均在冬季。目前尚无老年人血脂季节性变化的报告。鉴于老年人心血管病死亡率最高,因此,任何随季节变化的危险因素,对老年人群都极为重要。作者对一组65～74岁人群血脂的季节性变化进行了研究。方法随机选取96名自愿者(男47人、女49人,平均年龄69岁)参加此项研究。从91年1月至92年2月每隔2个月对受试者采血一次进行血脂测定,共7次。受试者不需空腹,从肘前静脉取血,不用止血带加压。但每次取血均在一天的同一时间和一周的同一天。TC、HDL—c和TG(甘油三酯)用标准实验室方法在Technicon分析仪上测定,LDL—C用Friedewald方法测定。
Gordon et al. Conducted a series of longitudinal studies on the seasonal changes of blood lipids in 35- to 59-year-olds and found that total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), and high density lipoprotein cholesterol Peaks are in winter. There are currently no reports of seasonal changes in blood lipids in the elderly. Given the highest cardiovascular mortality in the elderly, any risk factor that varies with the seasons is of crucial importance to the elderly. The authors studied the seasonal changes of blood lipids in a population of 65-74 years old. Methods A total of 96 volunteers (47 males and 49 females, average age, 69 years) were enrolled in this study. From January 1991 to February 1992 every two months, subjects took a blood lipid test, a total of 7 times. Subjects do not need fasting, take blood from the antecubital vein, without tourniquet pressure. But each time the blood is collected at the same time of the day and the same day of the week. TC, HDL-c and TG (triglycerides) were measured on a Technicon analyzer using standard laboratory methods and LDL-C was determined using the Friedewald method.