用倒转的自体大隐静作主动脉-冠状动脉旁路移植常易引起管腔狭窄或完全闭塞,发生的原因与管腔内压、管壁缺血、血栓形成或纤维素沉着、内皮和内膜缺血或受损后的修复等因素有关。本文描述血管移植后结构改变的状况,并对上述因素进行讨论。正常人体大隐静脉可分为内膜、中层、外膜三层。内膜由内皮细胞和纤维组织组成,在内膜与中层之间有一层弹力膜;中层由多层平滑肌细胞组成,中间被胶原束、基质和短 Inverted autosomaltic static aorto-coronary artery bypass graft often leads to stenosis or complete occlusion, the reasons for the occurrence of intraluminal pressure, wall ischemia, thrombosis or fibrosis, endothelium and internal Membrane ischemia or damaged after repair and other factors. This article describes the structural changes after vascular grafts, and discusses the above factors. Normal human saphenous vein can be divided into intima, middle and outer three layers. The intima consists of endothelial cells and fibrous tissue with a stretch of elastic membrane between the intima and the middle layer; the middle layer consists of multiple layers of smooth muscle cells surrounded by collagen bundles, matrix and short