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为了探讨成年大鼠坐骨神经（ＳＣＩ）去传入后初级体感皮层是否发生快速重组，在氯胺酮麻醉下，利用微电极测定后爪代表区，然后用普鲁卡因阻滞对侧ＳＣＩ。结果表明，阻滞后１ｈ、４ｈ和８ｈ，隐神经代表区（ＳＡＲ）比对照分别增大３２．５％（ｎ＝７）、９３．０％（ｎ＝１７）和１００％（ｎ＝４）。此外，在原ＳＡＲ和新生ＳＡＲ记录的平均多单位诱发反应的峰潜伏期，后者比前者延长４．３ｍｓ。作者推测在快速出现的皮层重组机制中，皮层－皮层多突触通路的去抑制可能起重要作用
To investigate whether rapid primary reorganization of primary somatosensory cortex following the introduction of sciatic nerve (SCI) into adult rats was performed, the representative area of the hind paw was measured by microelectrode under ketamine anesthesia, and contralateral SCI was blocked with procaine. The results showed that the areas of saphenous nerve increased by 32.5% (n = 7), 93.0% (n = 17) and 100% (n = 4) respectively at 1 h, 4 h and 8 h after the blockade ). In addition, the mean multi-unit evoked peak latency of the original SAR and the newborn SAR recorded a 4.3-ms increase over the former. The authors speculate that in the rapidly emerging cortical reorganization mechanism, the de-repression of cortical-cortical synaptophysiological pathways may play an important role