在一次性输液器辐射灭菌实践中,根据实际生产和辐射环境情况,选择对象菌及进行对象菌的辐射敏感性试验。针对柱状钴源结构和静态辐照方式的特点,为控制灭菌质量,进行了辐照场和产品箱内剂量分布和剂量均匀度等测量。最后,通过输液器材质辐照的理化性能测量、家兔热原试验和临床试用观测,证明本辐照装置、辐照工艺控制和该产品材料都能满足 灭菌和实用要求。 In one-time radiation sterilization practice, according to the actual production and radiation environment, choose the target bacteria and the radiation sensitivity of the target bacteria. In view of the characteristics of the columnar cobalt source structure and the static irradiation method, in order to control the sterilization quality, the dose distribution and the uniformity of the dose in the irradiation field and the product box were measured. Finally, through the physical and chemical properties measurement of infusor material irradiation, rabbit pyrogen test and clinical trial observation, it is proved that the irradiation device, the irradiation process control and the product material can meet the sterilization and practical requirements.