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作者对临床有肺水肿(端坐呼吸,紫绀,大汗和肺部啰音)的22例患者分为两组作了研究。在7例(A组)患者中,作了血液动力学的观察。在严重肺水肿的紧急情况下,测定肺动脉压力和心搏出量。舌下服硝酸甘油1.6mg后的10分钟内,左室充盈压从33±10下降至24±8mmHg,心搏出量显著增加,从3.3±0.8增至3.7±0.8L/分。新近心肌梗死的1例患者,5分钟内左室充盈压从50下降至27mmHg。端坐呼吸与肺部啰音迅速消失。在15例(B组)患者中,对临床经过作了观察和记录。这些患者接受1～6剂0.8～2.4mg硝酸甘
The authors of 22 patients with pulmonary edema (sitting breathing, cyanosis, sweating and pulmonary rales) were divided into two groups were studied. Hemodynamic observations were made in 7 patients (group A). Pulmonary artery pressure and stroke volume were measured in an emergency of severe pulmonary edema. Within 10 minutes of sublingual nitroglycerin 1.6 mg, left ventricular filling pressure decreased from 33 ± 10 to 24 ± 8 mmHg and cardiac output increased significantly from 3.3 ± 0.8 to 3.7 ± 0.8 L / minute. In 1 patient with a recent myocardial infarction, left ventricular filling pressure decreased from 50 to 27 mmHg in 5 minutes. Sitting breathing and lung rales disappear quickly. In 15 cases (group B) of patients, the clinical course was observed and recorded. These patients receive 1 to 6 doses of 0.8 to 2.4 mg of nitroglycerin