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本文讨论了慢性肝炎的发病原理及其治疗和预后的进展现状。一、慢性肝炎的病因及发病原理关于慢性肝炎的病因及发病原理,基本上可归纳为两种观点:自身免疫性疾病和肝炎病毒持续性感染。前者代表性的理论为Mackay 等提出的“狼疮样肝炎”学说;后者自发现HBAg 以来,慢性肝炎患者其HBAg常呈持续阳性,因此考虑病毒持续感染在慢性肝炎形成中起重要作用。究竟是哪一种或两种病因参与发病,目前尚不清楚。与自身免疫现象有关的慢性肝炎组和与HBAg 有关的慢性肝炎组,其表现差别甚大,有人认为
This article discusses the pathogenesis of chronic hepatitis and its treatment and prognosis of the status quo. First, the etiology and pathogenesis of chronic hepatitis Chronic hepatitis etiology and pathogenesis, basically can be summarized into two perspectives: autoimmune diseases and hepatitis virus persistent infection. The former is represented by the theory of “lupus-like hepatitis” proposed by Mackay et al. Since HBAg is the persistent HBAg in patients with chronic hepatitis, the persistent viral infection is considered to play an important role in the development of chronic hepatitis. It is not yet clear which one or both causes are involved. The performance of the chronic hepatitis group and the HBAg-related chronic hepatitis group, which are related to the autoimmune phenomenon, vary widely. Some people think