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目的 观察阻塞性睡眠呼吸暂停综合征 (OSAS)患者睡眠前后的血压变化。方法 对5 8例患者行多导睡眠图 (PSG)检查及睡前、睡醒后肘部血压测定 ,选取呼吸紊乱指数 (RDI)≥ 5的 34例OSAS患者为OSAS组 ,RDI <5的 2 4例为对照组 ,比较相关指标。结果 OSAS组睡眠前、睡醒后收缩压、舒张压比较差异有显著性 ,OSAS组醒后血压明显高于睡前血压 (P <0 .0 5 ) ,而对照组睡眠前后血压无明显变化 ,OSAS组最低血氧饱和度较对照组明显降低。结论 OSAS患者可出现睡醒后血压升高 ,这可能是部分高血压的病因 ,经鼻持续气道正压 (nCPAP)治疗有利于高血压的降低
Objective To observe the changes of blood pressure in obstructive sleep apnea syndrome (OSAS) patients before and after sleep. Methods Fifty-eight patients with OSAS underwent polysomnography (PSG) examination and elbow blood pressure measurement before going to sleep and waking up, OSAS patients with OSI ≥ 5 were selected as OSAS group, RDI <5 2 4 cases as control group, compare the relevant indicators. Results Before sleep, the systolic pressure and diastolic pressure of OSAS group were significantly different. Before and after sleep, the blood pressure of OSAS group was significantly higher than that before sleep (P <0.05), while the control group had no significant changes of blood pressure before and after sleep, OSAS group minimum oxygen saturation than the control group was significantly lower. Conclusion OSAS patients may have elevated blood pressure after waking up, which may be the cause of partial hypertension. Nasal continuous positive airway pressure (nCPAP) treatment is beneficial to the reduction of hypertension