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放射治疗对鼻咽癌是首选治疗方法,并有较好的疗效,5年生存率达45~49%,但首程放疗后仍有13%的病的局部未控,20~39%的病例局部复发。本文作者就鼻咽癌单纯足量首程放疗后联合腔内放射治疗,提高局部控制率做了近期疗效的报告。本组病例13人,外照射治疗后局部残留4例,联合腔内放射治疗后一月,局部消退率100%,三月后复查未见复发,同时指出外照射后CT显示咽旁无残留,无颅底骨质破坏,颈部淋巴结≤1.5cm,对腔内放疗有较好的适应症。足量外照射后1~2周开始腔内放疗,每次4~5Gy,共3~4次,放疗后局部反应轻,后遗症少,操作简便,鼻咽局部控制率好,生存质量高,值得推广。
Radiation therapy for nasopharyngeal carcinoma is the preferred treatment, and has a good effect, 5-year survival rate of 45 to 49%, but after the first run radiotherapy still 13% of the disease is not locally controlled, 20 to 39% of cases Local recurrence. The authors report on the short-term efficacy of nasopharyngeal carcinoma in combination with endovascular radiotherapy after first full-dose radiotherapy to improve the local control rate. The group of 13 patients, 4 cases of local residual after external beam irradiation, combined with endovascular radiotherapy in January, the local regression rate of 100%, no recurrence after the review in March, also pointed out that after external irradiation showed no residual parapharyngeal, No skull base bone destruction, cervical lymph node ≤ 1.5cm, better indication of intracavitary radiotherapy. 1 ~ 2 weeks after adequate external irradiation, intracavitary radiotherapy is started, 4 ~ 5 Gy each time for 3 ~ 4 times. After local radiotherapy, the local reaction is light with few sequelae and the operation is simple. The nasopharyngeal local control rate is good and the quality of life is high. Promotion.