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头颈部癌(HNC)的发病、病程及预后与机体免疫机能有密切联系。有人发现HNC病人术前若免疫反应正常,则术后效果好,表现恢复快,无复发,生存期长。免疫机能取决于免疫活性细胞的相互作用,依赖于细胞表面蛋白质分泌合成的表达方式,或称膜结合决定簇,其中糖蛋白起重要作用。非活化的T细胞不具备Ia抗原,缺乏对同种抗原的混合淋巴细胞反应的能力;活化T细胞则具备Ia抗原,其免疫功能不亚于T细胞亚群,参与免疫信息传递。本文研究了18例HNC病人T细胞的表现型。在体外观察植物血凝素刺激下
The incidence, duration and prognosis of head and neck cancer (HNC) are closely related to the immune function of the body. Some people found that HNC patients preoperative immune response if normal, the postoperative effect is good, the performance of rapid recovery, no recurrence, long survival. Immune function depends on the interaction of immunocompetent cells, on the expression of cell-surface protein synthesis, or membrane-bound determinants, of which glycoproteins play an important role. Non-activated T cells do not possess Ia antigen and lack the ability to react with mixed lymphocytes of alloantigens; activated T cells possess Ia antigen with immune function as much as T cell subsets and participate in immune message transmission. In this paper, 18 HNC patients T cell phenotype. In vitro observed phytohemagglutinin stimulation