目的:探讨卵巢肿瘤的内分泌检测及其临床意义。方法:对该院2005年1月～2010年1月300例卵巢肿瘤患者进行全套的内分泌检测,探讨其中孕激素与雌激素受体的表达及其临床意义。所有患者在检测前均未进行过卵巢肿瘤的手术、化疗、激素治疗等。使用免疫组化Envision二步法进行检测。结果:300例患者中,包括良性64例,交界性63例,恶性173例。雌激素阳性分别为7例、32例、110例。孕激素阳性率分别为22例、31例和70例。300例患者中,雌激素各组比较,差异明显,P<0.05;孕激素各组比较,P>0.05,差异无统计学意义。结论:卵巢肿瘤检测内分泌具有较大的临床价值,尤其在恶性肿瘤中阳性率较高。 Objective: To investigate the endocrine detection of ovarian tumors and its clinical significance. Methods: The hospital from January 2005 to January 2010 300 cases of ovarian cancer patients with a full set of endocrine tests to explore the progesterone and estrogen receptor expression and clinical significance. All patients had no ovarian tumor surgery, chemotherapy, hormone therapy before testing. Immunohistochemistry Envision two-step method for detection. Results: Of the 300 patients, 64 were benign, 63 were borderline, and 173 were malignant. Estrogen positive were 7 cases, 32 cases, 110 cases. Progesterone positive rates were 22 cases, 31 cases and 70 cases. 300 cases of estrogen in each group, the difference was significant, P <0.05; progesterone in all groups, P> 0.05, the difference was not statistically significant. Conclusion: The detection of endocrine ovarian tumors have great clinical value, especially in malignant tumors, a higher positive rate.