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[目的]探讨拇指桡背侧皮神经营养血管皮瓣修复拇指末节皮肤软组织缺损的方法及临床疗效.[方法]对16例拇指末节皮肤软组织缺损患者依据缺损面积大小设计拇指桡背侧皮神经营养血管皮瓣一期修复缺损创面,缺损面积为1.0 cm ×2.0 cm ~2.5 cm ×3.0 cm ,术中行皮神经和指神经端端吻合,术后常规抗感染及抗血管痉挛等治疗,密切观察皮瓣存活情况.随访3~6个月观察拇指外形及皮瓣感觉.[结果]16例患者皮瓣全部存活,伤口均一期愈合,随访3~6个月后拇指外观满意,皮瓣两点辨别觉5~10 mm ,感觉恢复好.[结论]拇指桡背侧皮神经营养血管皮瓣血供稳定,存活率高,供区损伤小,是修复拇指末节皮肤软组织缺损的一种可靠方法.“,”Objective] To explore the method and clinical efficacy of thumb radial dorsal cutaneous neuro‐vascular flap for repairing thumb distal skin and soft tissue defects .[Methods] According to the defect area size of patients with thumb distal skin and soft tissue defect ,thumb radial dorsal cutaneous neurovascular flap was designed for the one‐stage reparation of defect wound .The defect area was 1 .0 × 2 .0 cm ~ 2 .5 × 3 .0 cm . Intraoperative cutaneous nerve and digital nerve anastomosis were performed .Postoperative conventional anti‐infection and the treatment of vasospasm were taken .Skin flap survival was observed closely .Thumb shape and flap sensation during 3 ~ 6 months of follow up were observed .[Results] Skin flaps of 16 patients all sur‐vived .The wound all healed at one stage .After 3 ~ 6 months of follow up ,the appearance of the thumb was satisfied ,and the two‐point discrimination of flap was 5 ~ 10 mm .The sensation of flap recovered well .[Con‐clusion] Thumb radial dorsal cutaneous neurovascular flap has stable blood supply ,high survival rate and little damage of donor site ,so it is a reliable way to repair thumb distal skin and soft tissue defect .