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目的探讨热毒宁注射液佐治儿童急性病毒性下呼吸道感染的疗效。方法选择2009年3月至2010年3月潍坊医学院附属医院儿科住院的180例急性下呼吸道感染患儿。入院24h内检测7种常见呼吸道病毒,根据入院次序分成两组。在常规治疗基础上,治疗组加用热毒宁注射液0.5～0.8mL(/kg·d),对照组加用利巴韦林10mg(/kg·d),连用5d。结果 180例患儿病毒检测阳性率为61.7%(111/180),其中治疗组为63.3%,对照组为60.0%,差异无统计学意义(P>0.05)。治疗组退热、咳喘改善、肺部啰音消失时间以及住院天数等均短于对照组,差异有统计学意义(P均<0.05)。住院总费用两组比较差异无统计学意义(P>0.05)。结论热毒宁注射液佐治儿童急性病毒性下呼吸道感染疗效好且不增加患者经济负担。
Objective To investigate the therapeutic effect of Rendunning injection on children with acute viral lower respiratory tract infection. Methods From March 2009 to March 2010 weifang medical college hospital pediatric hospitalized 180 cases of acute lower respiratory tract infection in children. Seven kinds of common respiratory viruses were detected within 24 hours of admission and divided into two groups according to admission order. On the basis of routine treatment, the treatment group plus heat poisoning injection 0.5 ~ 0.8mL (/ kg · d), the control group plus ribavirin 10mg (/ kg · d), once every 5d. Results The positive rate of virus detection in 180 children was 61.7% (111/180), of which the treatment group was 63.3% and the control group was 60.0%, the difference was not statistically significant (P> 0.05). The treatment group fever, cough and asthma to improve, the disappearance of pulmonary rales and hospitalization days were shorter than the control group, the difference was statistically significant (P all <0.05). The total cost of hospitalization was no significant difference between the two groups (P> 0.05). Conclusion Revedun injection in children with acute viral respiratory tract infection is effective and does not increase the economic burden of patients.