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消炎痛是目前临床上广泛使用的非甾体解热镇痛药,对于类风湿性关节炎、风湿性关节炎及各种类型的关节病均有一定疗效。但由于片剂口服对胃肠道刺激性较大,易产生恶心、厌食、胃痛等不良反应,对胃炎或溃疡病患者不宜使用,慢性风湿病患者长期用药也受到一定限制。消炎痛栓的主要优点是改变了给药途径,经肛门给药,避免药物直接刺激胃肠道,减少副作用,保证用药安全,也扩大了使用范围。1977年,北京医院曾将消炎痛栓使用于门诊,随访观察163个病例,总有效率为83%,其中显效率为72%。临床印象,消炎痛栓剂与口服制剂相比,疗效无明显差异。消炎痛栓的特点是副作用小,维持时间
Indomethacin is currently widely used in clinical non-steroidal antipyretic analgesics, for rheumatoid arthritis, rheumatoid arthritis and various types of joint disease have a certain effect. However, due to tablet oral gastrointestinal irritation, easy to produce nausea, anorexia, stomach pain and other adverse reactions, should not be used for patients with gastritis or ulcer disease, chronic rheumatic patients with long-term medication is also subject to certain restrictions. The main advantage of indomethacin suppository is to change the route of administration, transanal administration, to avoid drugs directly stimulate the gastrointestinal tract, reduce side effects, to ensure drug safety, but also expanded the scope of use. In 1977, Beijing Hospital had indomethacin suppository used in the clinic, follow-up observation of 163 cases, the total effective rate was 83%, of which markedly effective rate was 72%. Clinical impression, indomethacin suppository compared with oral preparations, no significant difference in efficacy. Indometacin is characterized by small side effects, to maintain time