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目的:分析南京地区儿童急性呼吸道感染病毒病原学检查结果,了解呼吸道病毒流行情况,为临床病毒病原学诊断、治疗提供依据。方法:取7459例急性呼吸道感染儿童鼻咽分泌物,采用直接免疫荧光法检测7种常见呼吸道病毒抗原。结果:我院三年中有3745份标本病毒检测阳性,主要是呼吸道合胞病毒(RSV)2305例,副流感病毒3型(PIV3)511例;病毒检出率在婴儿组和幼儿组较高,分别为55.82%和50.98%;冬季病毒检出率最高为69.26%;所致疾病以支气管肺炎最为多见。结论:2009年-2011年南京地区急性呼吸道感染的病毒仍以RSV为主要病原体,婴儿病毒感染率较高,儿童呼吸道病毒感染好发于冬季。
Objective: To analyze the etiological diagnosis of acute respiratory infection in children in Nanjing and to understand the prevalence of respiratory viruses, so as to provide basis for the diagnosis and treatment of clinical viral etiology. Methods: Nasopharyngeal secretions were collected from 7459 children with acute respiratory tract infection and 7 common respiratory virus antigens were detected by direct immunofluorescence assay. Results: There were 3,745 positive specimens in our hospital in three years, mainly including 2305 cases of respiratory syncytial virus (RSV) and 511 cases of parainfluenza virus type 3 (PIV3). The detection rate of virus in infants and children was higher , Respectively 55.82% and 50.98%; winter virus detection rate was 69.26%; the most common cause of bronchial pneumonia. CONCLUSIONS: RSV is still the major causative agent of acute respiratory infections in Nanjing from 2009 to 2011. The prevalence of virus infection in infants is high, and respiratory virus infection in children occurs in winter.