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目的探讨分析胰岛素增敏剂联合达英-35应用于多囊卵巢综合征中的治疗效果。方法选择于2011年3月~2013年4月在我院接受治疗的多囊卵巢综合征患者112例,随机分成对照组与观察组各56例,对照组患者应用达英-35单独治疗,观察组患者联合胰岛素增敏剂治疗,通过观察BMI、WHR与体重以及优势卵泡出现率、子宫内膜发育情况、卵巢过度刺激综合征出现情况与妊娠率比较两组治疗方式的临床效果。结果治疗结果显示两组患者的BMI、WHR与体重均一定程度降低,但观察组患者的降低幅度更为明显;同时观察组患者在优势卵泡出现率、子宫内膜发育情况、卵巢过度刺激综合征出现情况以及妊娠率方面显著优于对照组,两组比较差异显著(P<0.05),具有统计学意义。结论多囊卵巢综合征应用胰岛素增敏剂联合达英-35治疗的模式能够改善患者的临床体征,促进排卵、提高妊娠率,具有十分重要的临床意义,值得临床推广应用。
Objective To investigate the therapeutic effect of insulin sensitizer combined with da-Ying-35 in polycystic ovary syndrome. Methods One hundred and twelve patients with polycystic ovary syndrome who were treated in our hospital from March 2011 to April 2013 were randomly divided into control group and observation group with 56 cases in each group. Group of patients combined insulin sensitizer treatment, by observing the BMI, WHR and body weight, as well as the incidence of dominant follicles, endometrial development, ovarian hyperstimulation syndrome and pregnancy rates were compared between two groups of clinical effects. Results The results of treatment showed that the BMI, WHR and body weight of both groups decreased to a certain degree, but the decrease of observation group was more obvious. At the same time, the prevalence of dominant follicles, endometrial development, ovarian hyperstimulation syndrome Occurrence and pregnancy rate were significantly better than the control group, the difference between the two groups was significant (P <0.05), with statistical significance. Conclusion Polycystic ovary syndrome with insulin sensitizer combined with da-Ying -35 treatment can improve the patient’s clinical signs, promote ovulation and improve pregnancy rate, has a very important clinical significance, is worthy of clinical application.