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目的探讨华蟾素注射液治疗晚期消化系统恶性肿瘤患者的疗效。方法选取2015年7月至2016年8月于辽宁省鞍山市肿瘤医院接受治疗的30例晚期消化系统恶性肿瘤患者作为研究对象,随机分为观察组和对照组,各15例。对照组患者采取基础性治疗,观察组患者在对照组治疗基础上采用华蟾素注射液进行治疗,比较两组患者瘤体疗效、体力状况及癌症疼痛控制情况。结果在瘤体疗效方面,观察组患者的临床有效率为73.3%,明显高于对照组的20.0%,差异有统计学意义(P<0.05);在体力状况方面,观察组患者中稳定患者占66.7%,对照组患者中稳定患者占46.7%,观察组显著高于对照组,差异有统计学意义(P<0.05);在癌症疼痛控制方面,观察组患者治疗的有效率为86.7%,对照组为26.7%,观察组高于对照组,差异有统计学意义(P<0.05)。结论华蟾素注射液治疗消化系统恶性肿瘤效果显著,对于恶性肿瘤的抑制、患者身体状况改善以及治疗过程中所承受的痛苦减轻均有明显作用。
Objective To investigate the efficacy of cinobufacini injection in patients with advanced digestive system malignancies. Methods Thirty patients with advanced digestive system malignant tumor treated at Anshan Cancer Hospital of Liaoning Province from July 2015 to August 2016 were randomly divided into observation group and control group, 15 cases each. Patients in the control group took basic treatment. Patients in the observation group were treated with cinobufacini injection on the basis of the control group. The curative effect, physical condition and control of cancer pain were compared between the two groups. Results The clinical efficacy of the observation group was 73.3%, which was significantly higher than that of the control group (20.0%), the difference was statistically significant (P <0.05); in the physical condition, the stable patients in the observation group accounted for 66.7%, 46.7% of stable patients in the control group, the observation group was significantly higher than the control group, the difference was statistically significant (P <0.05); in the control of cancer pain, the observation group patients treatment efficiency was 86.7% Group was 26.7%, the observation group was higher than the control group, the difference was statistically significant (P <0.05). Conclusion Cinobufacini injection has significant effect in treating digestive system malignancies and has obvious effect on the suppression of malignant tumors, improvement of patients’ condition and alleviation of pain during the course of treatment.