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本研究对象为32例年龄均小于66岁的急性心肌梗塞(AMI)患者,发病后平均2小时入院。根据室性心律失常的种类和严重程度分为3组:①室性心动过速(VT)组:14例,其中13例为非持续性 VT(室性异位搏动连续3～20次);1例为持续性 VT(持续1/2min 以上),共发作2次,其中1次发展为室颤,导致意识、脉搏及呼吸消失,2次均经电击而复律。③频发室性期前收缩(≥5/min)组:8例。③偶发室性期前收缩(≤4/min)组:10例。结果入院时各组平均心率及 QT 间期无显著差别,但按心率纠正后的 QT 间期(QTc)则①组较②、③组显著延长(P<0.001),分别为0.52±0.07sec、0.47±0.03 sec 及0.46±0.03sec。此外,在入院后第5天,仅 VT 组平均 QTc 明显缩短,从0.52±0.07
The subjects were 32 AMI patients younger than 66 years of age who were admitted to the hospital on average 2 hours after onset. According to the type and severity of ventricular arrhythmias, the patients were divided into 3 groups: (1) ventricular tachycardia (VT) group: 14 cases, of which 13 cases were non-persistent VT (ventricular ectopic beats 3 to 20 times in a row); 1 case of persistent VT (continued for more than 1 / 2min), a total of 2 times, of which 1 developed ventricular fibrillation, resulting in awareness, pulse and respiration disappeared, 2 times by electrical shock and cardioversion. ③ frequent ventricular contraction (≥ 5 / min) group: 8 cases. ③ occasional ventricular contraction (≤ 4 / min) group: 10 cases. Results There was no significant difference in mean heart rate and QT interval between the two groups at admission, but the QT interval corrected by heart rate (QTc) was significantly longer (P <0.001) than that in group② and group③ (0.52 ± 0.07sec, 0.47 ± 0.03 sec and 0.46 ± 0.03 sec. In addition, on day 5 after admission, mean QTc was significantly shorter in the VT group alone, from 0.52 ± 0.07