论文部分内容阅读
本文研究了医用皮乐宝洗剂中皮乐宝含量的测定方法。皮乐宝洗剂不需经压何前处理,直接进入反相ODS柱,用甲醇和含离子对试剂PICB-5的水进行等梯度洗脱,紫外254nm检测,该法简便、快速,皮乐宝的回收率为98.9％。变异系数为0.4—0.5％. 皮乐宝(Bronopol)为溴硝丙二醇(2-Bromo-2-nitro-1,3-propandiol)的俗称,用它和某些辅料配成的水溶液是一种新型抗革兰氏阴性细菌特别是绿脓杆菌以及其它假单胞菌的外用洗剂,对革兰氏阳性细菌和真菌也有抑制作用。国外已将它广泛运用于烫伤、褥疮、手术后肉芽疮、瘘孔、脓疡等症的治疗,以及皮肤表面消毒及器械消毒等。
This paper studies the determination of Pipo in medical skincare lotion. Plover lotion without pressure before any treatment, direct access to the reversed phase ODS column, with methanol and ion-containing reagent PICB-5 water gradient elution, UV 254nm detection, the method is simple, fast, Po’s recovery rate was 98.9%. The coefficient of variation is 0.4-0.5%. Bronopol is a common name for 2-Bromo-2-nitro-1,3-propandiol. It is a new type of aqueous solution Gram-negative bacteria, especially Pseudomonas aeruginosa and other topical lotion Pseudomonas, also have positive effects on Gram-positive bacteria and fungi. Abroad has been widely used in scald, pressure sores, postoperative granulation, fistula, abscess embolism treatment, as well as the skin surface disinfection and equipment disinfection.